New research shows that gaining weight may actually be all in your genes.




Obesity is generally blamed on bad diet and a sedentary lifestyle - but new research shows that gaining weight may actually be all in your genes.
---So Mcdonalds Burgers are healthy for you (sarcasm)
According to results published in the journal Nature, more than 100 locations across the genome play a role in various obesity traits.
This discovery could possibly help doctors develop better weight-loss therapies for their patients that don't just include diet and exercise, writes Nature World News.
"Our work clearly shows that predisposition to obesity and increased body mass index is not due to a single gene or genetic change," senior study author Elizabeth Speliotes, with the University of Michigan Health System, said in a statement.
"The large number of genes makes it less likely that one solution to beat obesity will work for everyone and opens the door to possible ways we could use genetic clues to help defeat obesity," she added.
Researchers measured the body mass index (BMI) of nearly 340,000 people for  - then compared it with their genetic makeup.
They found 97 sites associated with obesity - three times as many than scientists had previously estimated.
It is well documented that obesity can lead to all sorts of metabolic conditions, including type 2 diabetes.
Fat deposits, which can build up around the abdomen - creating the "muffin top" or "beer belly" - increases the risk of cardiovascular diseases.
"If we can figure out which genes influence where fat is deposited, it could help us understand the biology that leads to various health conditions, such as insulin resistance/diabetes, metabolic syndrome, and heart disease," explained researcher Karen Mohlke, who worked on a related study.
The researchers also note that while some genes involved in obesity may already be implicated in other aspects of human health, others could be part of pathways that are yet to be established by researchers.
Scientists still have a long way to go before they fully understand the link between the human genome and obesity, but further research hopefully will show how these genes play a part in various diseases.
"A major challenge now is learning about the function of these genetic variations and how they indeed increase people's susceptibility to gain weight," senior author Ruth Loos added.
"This will be the critical next step, which will require input from scientists with a range of expertise, before our new findings can be used towards targeted obesity prevention or treatment strategies."

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